Name | Dithioerythritol |
Synonyms | DTE Dithioerythritol Dithioerythritol DTE 1,4-dithio-erythrito (S,R)-DITHIOERYTHRITOL DITHIOERYTHRITOL SIGMAULTRA 1,4-dimercapto-,(r*,s*)-3-butanediol erythro-1,4-Dimercapto-2,3-butanediol (r*,s*)-1,4-dimercapto-2,3-butanediol (2R,3S)-1,4-disulfanylbutane-2,3-diol 1,4-dimercapto-,(theta,s)-3-butanediol 1,4-Dimercapto-2,3-butanediol, erytho-Form DITHIOERYTHRITOL MOLECULAR BIOLOGY*REAGE NT Dithioerythritol, Molecular Biology Grade DTE, Molecular Biology Grade |
CAS | 6892-68-8 |
EINECS | 229-998-8 |
InChI | InChI=1/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+ |
InChIKey | VHJLVAABSRFDPM-ZXZARUISSA-N |
Molecular Formula | C4H10O2S2 |
Molar Mass | 154.25 |
Density | 1.156 (estimate) |
Melting Point | 82-84°C(lit.) |
Boling Point | 247.65°C (rough estimate) |
Flash Point | 174.2°C |
Water Solubility | Soluble |
Solubility | Soluble in water. |
Vapor Presure | 8.68E-07mmHg at 25°C |
Appearance | White solid |
Color | White to pale yellow or beige |
Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.400', , 'λ: 280 nm Amax: 0.050'] |
BRN | 1719756 |
pKa | pK1:9.5 (25°C) |
PH | 4.0-6.0 (25℃, 0.1M in H2O) |
Storage Condition | 2-8°C |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
Sensitive | Air Sensitive |
Refractive Index | 1.5200 (estimate) |
MDL | MFCD00063750 |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
UN IDs | UN 3335 |
WGK Germany | 3 |
RTECS | KF2410000 |
FLUKA BRAND F CODES | 3-10-13-23 |
TSCA | Yes |
HS Code | 29309070 |
Hazard Class | 9 |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Overview | dithiotriol, also known as dithiotriol (DTE), is dithiothreitol (DTT) A stereoisomer. The two hydroxyl groups of DTT are in the threo configuration and the two hydroxyl groups of DTE are in the red configuration. |
Application | , DTE can be used as a reducing agent and a deprotecting agent for thiolated DNA, and is also commonly used in the reduction of disulfide bonds in proteins, used to prevent the formation of intramolecular or Intermolecular disulfide bonds between cysteines in proteins.|
biological activity | DTE (Dithioerythritol) is a sulfur-containing sugar derived from the corresponding 4-carbon monosaccharide erythrose; it is an episomer of dithiothreitol (DTT). |
Use | reagents for reduction of Thiol or disulfide bonds in biochemical studies. |